Intensification Of Bioactive Compounds Extraction From Medicinal Plants Using Ultrasonic Irradiation.

Extraction processes are largely used in many chemical, biotechnological and pharmaceutical industries for recovery of bioactive compounds from medicinal plants. To replace the conventional extraction techniques, new techniques as high-pressure extraction processes that use environment friendly solvents have been developed. However, these techniques, sometimes, are associated with low extraction rate. The ultrasound can be effectively used to improve the extraction rate by the increasing the mass transfer and possible rupture of cell wall due the formation of microcavities leading to higher product yields with reduced processing time and solvent consumption. This review presents a brief survey about the mechanism and aspects that affecting the ultrasound assisted extraction focusing on the use of ultrasound irradiation for high-pressure extraction processes intensification.888-9

Optimization and economic evaluation of pressurized liquid extraction of phenolic compounds from jabuticaba skins

AbstractThe optimization of the extraction of anthocyanins and other phenolic compounds from jabuticaba skins, a promising Brazilian source of these compounds, was studied using pressurized liquid extraction (PLE). An optimization study was performed using ethanol as a solvent and with extraction pressure (5–10MPa), temperature (313–393K) and static extraction time (3–15min) as independent variables. The optimum PLE conditions for all response variables were estimated; however, PLE conditions resulting in the highest recovery of anthocyanins (5MPa, 553K and 9min of static extraction time) were chosen for comparison with a conventional low-pressure solvent extraction (LPSE). The attributes compared were yield, content of anthocyanins and phenolic compounds and economic feasibility. Similar extraction yields were obtained by LPSE and PLE under optimized conditions; however 2.15 and 1.66-fold more anthocyanins and total phenolic compounds, respectively, were extracted using PLE, while the cost of manufacturing (COM) obtained for the PLE extract was 40-fold lower

Sex-specific genetic effects in physical activity: results from a quantitative genetic analysis

Background: The objective of this study is to present a model to estimate sex-specific genetic effects on physical activity (PA) levels and sedentary behaviour (SB) using three generation families. Methods: The sample consisted of 100 families covering three generations from Portugal. PA and SB were assessed via the International Physical Activity Questionnaire short form (IPAQ-SF). Sex-specific effects were assessed by genotype-by-sex interaction (GSI) models and sex-specific heritabilities. GSI effects and heterogeneity were tested in the residual environmental variance. SPSS 17 and SOLAR v. 4.1 were used in all computations. Results: The genetic component for PA and SB domains varied from low to moderate (11 % to 46 %), when analyzing both genders combined. We found GSI effects for vigorous PA (p = 0.02) and time spent watching television (WT) (p \u3c 0.001) that showed significantly higher additive genetic variance estimates in males. The heterogeneity in the residual environmental variance was significant for moderate PA (p = 0.02), vigorous PA (p = 0.006) and total PA (p = 0.001). Sex-specific heritability estimates were significantly higher in males only for WT, with a male-to-female difference in heritability of 42.5 (95 % confidence interval: 6.4, 70.4). Conclusions: Low to moderate genetic effects on PA and SB traits were found. Results from the GSI model show that there are sex-specific effects in two phenotypes, VPA and WT with a stronger genetic influence in males

Antioxidantes naturais: a vitamina C como projeto de ensino de Química em uma Feira de Ciências no Ensino Médio.

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Aspectos da cultura do estado de Goiás

ResumoO conceito de cultura abrange vários e diferentes aspectos. A respeito da cultura goiana, a raiz atrelada ao campo traduz o modo de falar, se portar e se vestir, além de repercutir nas tradições, festas, rituais, símbolos – compondo a sua memória e identidade. Porém, devido à modernização dos meios de produção e do modo de vida caipira, a raiz da identidade cultural goiana corre o risco de desaparecer sem ter sido amplamente conhecido pela comunidade. Nesse sentido, tem-se por objetivo apresentar um esboço descritivo a respeito dos principais aspectos da cultura do estado de Goiás. Para desenvolvimento do trabalho, foi utilizada a técnica documentação indireta referente à pesquisa documental e bibliográfica. Os aspectos culturais do Estado de Goiás são bem diversificados, representados por diversas por modalidades e vários seguimentos, como a música, as artes plásticas, as danças, as festas, a gastronomia, as lendas e o próprio modo de se comunicar (a fala). Estes aspectos compõem a estruturação e formação cultural de um Estado.Palavras-chave: Cultura, Goiás, Aspectos, Culturais, Geografia. AbstractThe concept of culture encompasses many different aspects. Regarding the culture of Goiás, the root linked to the field translates the way of speaking, behaving and dressing, as well as reverberating in traditions, festivals, rituals, symbols - composing their memory and identity. However, due to the modernization of the means of production and the country way of life, the root of the cultural identity of Goiás is in danger of disappearing without being widely known by the community. In this sense, this work aim to present a descriptive sketch about the main aspects of the culture of the state of Goiás. For the development of the work, the technique indirect documentation related to documentary and bibliographic research was used. The cultural aspects of the State of Goiás are well diversified, represented by diverse forms and various followings, such as music, plastic arts, dances, festivals, gastronomy, legends and the way of communicating itself (speech). These aspects make up the structuring and cultural formation of a State.Key-words: Culture, Goias, Aspects, Cultural, Geography

28 -- 40 GHz variability and polarimetry of bright compact sources in the QUIJOTE cosmological fields

We observed 51 sources in the Q-U-I JOint TEnerife (QUIJOTE) cosmological fields which were brighter than 1 Jy at 30 GHz in the Planck Point Source Catalogue (version 1), with the Very Large Array at 28 -- 40 GHz, in order to characterise their high-radio-frequency variability and polarization properties. We find a roughly log-normal distribution of polarization fractions with a median of 2%, in agreement with previous studies, and a median rotation measure (RM) of $\approx$ 1110 rad m$^{-2}$ with one outlier up to $\approx$ 64000 rad m$^{-2}$ which is among the highest RMs measured in quasar cores. We find hints of a correlation between the total intensity flux density and median polarization fraction. We find 59% of sources are variable in total intensity, and 100% in polarization at $3\sigma$ level, with no apparent correlation between total intensity variability and polarization variability. This indicates that it will be difficult to model these sources without simultaneous polarimetric monitoring observations and they will need to be masked for cosmological analysis.Comment: 17 pages, 14 figures, accepted to MNRA

Profile of Self-Care Capacity and Alcohol Use in Elderly Brazilians during the COVID-19 Outbreak: An Online Study

Background: Preventive and positive online coping strategies are essential for harm reduction associated with alcohol abuse among older adults in pandemic and social isolation scenarios. The objectives were to examine the relationship between alcohol use/abuse and physical capacity/self-care to perform the physical activities of daily living or impairment of the functional capacity of the elderly in the COVID-19 pandemic. Methods: An online cross-sectional survey was carried out. One hundred and one elderly people in the city of São Paulo, Brazil, participated in a community program. Results: Most participants (52.5%) showed excellent self-care skills. Approximately 12% of participants reported problems related to alcohol use/abuse. There was no association between self-care ability and abuse and probable alcohol dependence. Conclusions: Although most participants have excellent self-care and functional capacity and have not evidenced alcohol use/abuse, health professionals need to systematically provide information to prevent alcohol abuse, especially in scenarios of great emotional distress, such as in a pandemic. In addition, the online meetings held by the UAPI program were shown to be opportunities for social interaction and were essential to minimize the negative effects of the possible presence of alcohol use/abuse and the deteriorating performance of physical activities of daily living during a pandemic outbreak for the elderly

Null Models of Economic Networks: The Case of the World Trade Web

In all empirical-network studies, the observed properties of economic networks are informative only if compared with a well-defined null model that can quantitatively predict the behavior of such properties in constrained graphs. However, predictions of the available null-model methods can be derived analytically only under assumptions (e.g., sparseness of the network) that are unrealistic for most economic networks like the World Trade Web (WTW). In this paper we study the evolution of the WTW using a recently-proposed family of null network models. The method allows to analytically obtain the expected value of any network statistic across the ensemble of networks that preserve on average some local properties, and are otherwise fully random. We compare expected and observed properties of the WTW in the period 1950-2000, when either the expected number of trade partners or total country trade is kept fixed and equal to observed quantities. We show that, in the binary WTW, node-degree sequences are sufficient to explain higher-order network properties such as disassortativity and clustering-degree correlation, especially in the last part of the sample. Conversely, in the weighted WTW, the observed sequence of total country imports and exports are not sufficient to predict higher-order patterns of the WTW. We discuss some important implications of these findings for international-trade models.Comment: 39 pages, 46 figures, 2 table

The XMM Cluster Survey: The Stellar Mass Assembly of Fossil Galaxies

This paper presents both the result of a search for fossil systems (FSs) within the XMM Cluster Survey and the Sloan Digital Sky Survey and the results of a study of the stellar mass assembly and stellar populations of their fossil galaxies. In total, 17 groups and clusters are identified at z < 0.25 with large magnitude gaps between the first and fourth brightest galaxies. All the information necessary to classify these systems as fossils is provided. For both groups and clusters, the total and fractional luminosity of the brightest galaxy is positively correlated with the magnitude gap. The brightest galaxies in FSs (called fossil galaxies) have stellar populations and star formation histories which are similar to normal brightest cluster galaxies (BCGs). However, at fixed group/cluster mass, the stellar masses of the fossil galaxies are larger compared to normal BCGs, a fact that holds true over a wide range of group/cluster masses. Moreover, the fossil galaxies are found to contain a significant fraction of the total optical luminosity of the group/cluster within 0.5R200, as much as 85%, compared to the non-fossils, which can have as little as 10%. Our results suggest that FSs formed early and in the highest density regions of the universe and that fossil galaxies represent the end products of galaxy mergers in groups and clusters. The online FS catalog can be found at http://www.astro.ljmu.ac.uk/~xcs/Harrison2012/XCSFSCat.html.Comment: 30 pages, 50 figures. ApJ published version, online FS catalog added: http://www.astro.ljmu.ac.uk/~xcs/Harrison2012/XCSFSCat.htm